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--> Postdoctoral Researcher in Cancer Signaling and TherapeuticsThe Knight Cancer Institute is the sole NCI-designated Cancer Center, and the premier biomedical academic institution in Oregon. At the Knight Cancer Institute, we see a world without cancer. As pioneers in personalized cancer medicine, we continue to change the way the world understands and fights this disease. Work with us to develop new precision cancer therapies. Join us to create groundbreaking laboratory tests to identify unique characteristics of each patient’s tumor. Together, our efforts will provide individually tailored, compassionate care for every patient, from diagnosis through survivorship. We are situated in Portland: the gateway to Pacific Northwest, with easy access to the Pacific Ocean and the Cascade mountain ranges. The temperate climate, no sales tax and affordable cost of living, makes Portland an ideal place to work and live. Position Description: The Thomas Laboratory is interested in identifying the mechanisms of tumor responses to targeted therapy in cancer. Previous publications from our group include: Nature Medicine 12, 122-127; Cancer Journal 15, 406-420; Science Translational Medicine 3(85): 85ra47. A postdoctoral position is available for a highly motivated candidate with a background in molecular/cellular biology and/or genetics to join our NIH-funded research group. Evaluation of gene function and key signaling events will include the use of in vitro assays and mouse models; however, special emphasis will be placed on increasing the relevance of experimental findings to human cancer by validating potential therapeutic targets using primary patient samples and in vivo xenograft models. The successful applicant will be responsible for performing experiments in the laboratory which will include DNA, RNA, Protein extraction, Western blotting, Q-Real Time PCR, Tissue culture, Transfections, Chromatin Immunoprecipitation, Site Directed Mutagenesis, etc as well carry out data analysis resulting from experiments and help with manuscript preparation/writing. Job Requirements: Requirements include a PhD degree in Biology/ Molecular Biology/Genetics; excellent written and verbal communication; effective judgment and problem solving with little or no supervision is imperative in all facets of this position; highly motivated and committed to academic biomedical research; expertise in Excel, Graph Pad Prism and other bioinformatics analysis software such as BLAST; strong attention to detail, multi-tasking; and a willingness to learn new technologies. Applicants need to be already residing in the USA. One year of experience is strongly preferred. How To Apply: For more information and to apply online visit http://www.OHSUjobs.com and reference IRC38190. Please upload a cover letter, resume and contact information for three academic/professional references. Contact: George Thomas Knight Cancer Institute Oregon Health & Science University Center for Health & Healing 3303 SW Bond Avenue Portland, OR 97239 United States
